On average, even with the right antiviral therapy, it takes about 12 years for HIV patients to develop AIDS. HIV also encourages various pathologies and increases body’s vulnerability to bacterial infections. In case there is an infectious disease caused by bacteria, doctors can prescribe antibiotics for HIV patients. Antibiotic treatment impact gut flora and usually require a course of probiotics to restore it.
Every infectious disease calls for an individual approach to treatment. Depending on the nature of the pathogen, certain antibiotics are prescribed for HIV patients. Bacterial pneumonia in HIV-infected patients is more common than in the rest of the population. Even after recovery, as in the case of pneumocystis pneumonia, it leaves scarring in the lungs leading to restrictive breathing disorders for years.
The statistics show that bacterial pneumonia in HIV-infected is approximately 100 cases per 1000 HIV-infected patients per year. In fact, pneumonia is 7,8 times higher compared to the non-infected population. Bacterial pneumonia often develops at early stages of HIV infection. When the immune deficiency gets worse, there is the higher risk of infection.
When choosing drugs for the treatment of pneumonia in HIV patients, doctors should remember that the most likely pathogens are S. pneumonia and H. influenza. Bacterial pneumonia significantly worsens the long-term prognosis. That’s why recurrent bacterial pneumonia (more than one per year) is considered to be an AIDS-indicative disease.
The Protocol of Regional Office for Europe (2006) of the World Health Organization recommends that a child with symptoms of pulmonary infection (fever, cough, lung rales, radiographic changes) should be immediately prescribed with broad-spectrum antibiotics in general and Amoxicillin in particular.
The method of antibiotic administration depends on the patient’s condition. Usually, it is prescribed for an extended treatment during 10-14 days.
Patients with pneumonia should be carefully monitored. Clinical measures (temperature reduction, laboratory data, respiratory symptoms) are usually observed 48-72 hours after the start of therapy. Later, the X-ray image is taken to confirm the positive dynamics. If the condition deteriorates and there is no improvement within 24-72 hours, the diagnosis should be reconsidered, and alternative antibiotics with broader spectrum should be prescribed. For HIV patients, Amoxil does not interfere with the results of the immune function analysis.